Cart
sales@molnova.com
Home - Products - Apoptosis - Caspase - Taurohyodeoxycholic acid sodium salt

Taurohyodeoxycholic acid sodium salt

CAS No. 110026-03-4

Taurohyodeoxycholic acid sodium salt( Taurodeoxychloic Acid sodium hydrate | Sodium taurodeoxycholate monohydrate )

Catalog No. M21204 CAS No. 110026-03-4

Taurohyodeoxycholic acid sodium salt a hydrophilic bile salt on bile salt and biliary lipid secretion in the rat.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 56 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Taurohyodeoxycholic acid sodium salt
  • Note
    Research use only, not for human use.
  • Brief Description
    Taurohyodeoxycholic acid sodium salt a hydrophilic bile salt on bile salt and biliary lipid secretion in the rat.
  • Description
    Taurohyodeoxycholic acid sodium salt a hydrophilic bile salt on bile salt and biliary lipid secretion in the rat.
  • In Vitro
    Cell Proliferation Assay Cell Line:IEC-6 and caco-2 cells Concentration:0, 0.05, 0.50, and 1.00 mM Incubation Time:1, 2, 4 and 6 days Result:Significantly stimulated intestinal epithelial cell proliferation in a dose-dependent manner. Cell Cycle Analysis Cell Line:IEC-6 cells Concentration:0, 0.05, 0.50, and 1.00 mM Incubation Time:24 hResult:Significantly increased cells in S phase and decreased cells in G1-phase.Western Blot Analysis Cell Line:IEC-6 cells Concentration:0.5 mM Incubation Time:1 and 6 days Result:Significantly increased c-myc protein expression.
  • In Vivo
    Animal Model:C57BL/6N mice, Lipopolysaccharides (HY-D1056) injection model of sepsis Dosage:0.5 mg/kg Administration:Intravenous injection, 30 min or 24 h after LPS injection Result:Improved the survival rate of mice with sepsis. Decreased liver and kidney damage in septic mice. Ameliorated systemic inflammation and normalized blood pressure in septic mice.
  • Synonyms
    Taurodeoxychloic Acid sodium hydrate | Sodium taurodeoxycholate monohydrate
  • Pathway
    Apoptosis
  • Target
    Caspase
  • Recptor
    Caspase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    110026-03-4
  • Formula Weight
    540.71
  • Molecular Formula
    C26H47NNaO7S+
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (231.18 mM)
  • SMILES
    C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@@H]2[C@]1(CC[C@H]3[C@H]2C[C@@H]([C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na+]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Angelico M Baiocchi L Nistri A et al. Effect of taurohyodeoxycholic acid a hydrophilic bile salt on bile salt and biliary lipid secretion in the rat[J]. Digestive Diseases & Sciences 1994 39(11):2389-2397.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Z-VAD-FMK

    Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor, blocks all features of apoptosis.

  • Gypenoside XVII

    Gypenoside XVII confers protection against Aβ25-35-induced neurotoxicity through estrogen receptor-dependent activation of PI3K/Akt pathways, activation of Nrf2/ARE/HO-1 and inactivation of GSK-3β pathways.

  • Ac-FLTD-CMK

    Ac-FLTD-CMK is an inhibitor derived from abscisicin D (GSDMDD) with specific inhibitory effects on inflammatory caspases. ac-FLTD-CMK showed inhibitory effects on caspases-1, caspases-4 and caspases-11 with IC50s of 46.7 nM, 1.49 μM and 329 nM, respectively. Ac-FLTD-CMK showed potency against caspases-1, caspases-4 and caspases-11, but not against apoptosis-associated caspase-3.

Sign In Join Free